How do I clear the CMOS to reset BIOS settings on the PRIME B660-PLUS D4?

To clear the CMOS, turn off the computer and unplug the power cord, then use a metal object such as a screwdriver to short the two pins on the Clear CMOS header (CLRTC). Plug the power cord back in, turn on the computer, and hold down the Del key during boot to re-enter data in BIOS Setup. If this does not help, remove the onboard battery, short the two pins again, then reinstall the battery after clearing.

From the official ASUS Prime B660 Plus D4 Motherboard manual, page 14

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