What is the difference between the TH8110U, TH8320U, and TH8321U models?
The TH8110U supports 1 Heat/1 Cool systems, the TH8320U supports up to 3 Heat/2 Cool systems, and the TH8321U supports up to 3 Heat/2 Cool systems with the addition of dehumidification capability. All three are part of the VisionPRO TH8000 Series touch-screen programmable thermostats. (Page 1)
From the official Honeywell Th8320U1008 Thermostat manual, page 1
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