Is there a safety warning I should know about when lifting the handle during brewing?

Yes, there is an important caution: while brewing, there is extremely hot water in the K-Cup pod holder. To avoid injury, do not lift the handle during the brewing process. You should wait until brewing is complete, indicated when the buttons are no longer illuminated, before lifting the handle. (Page 6)

From the official Keurig K-Supreme Plus SKS910BK Coffee Maker manual, page 6

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