How do I update the BIOS using a USB flash drive without a CPU installed?

Download the latest BIOS file from the MSI website, rename it to MSI.ROM, and save it to the root of a USB flash drive. Connect the power supply to CPU_PWR1 and ATX_PWR1 (no CPU or memory needed), plug the USB drive into the Flash BIOS Port on the rear I/O panel, then press the Flash BIOS Button. The LED will flash during the process and turn off when complete. (Page 48)

From the official Msi B550M Pro VDH WiFi Motherboard manual, page 48

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