How do I set up a daily heating and cooling schedule?

Press Menu, select PROG, and turn it ON. You can program four time periods each day (Wake, Away, Home, and Sleep) with different settings for weekdays and weekends. Set the start time and both heat and cool temperature setpoints for each period, then press Home to save.

From the official Honeywell T4 Pro Programmable Thermostat (TH4110U2005/U) manual, page 3

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