Can I use the IQOS Iluma Prime in wet conditions or clean it with cleaning agents?

No, the IQOS Iluma Prime, Power Adaptor, and Charging Cable should not be exposed to any liquid, and you should not touch them if they become wet or have been immersed in liquid. You must not clean the device with any cleaning agent, but you should periodically clean the USB charging port to avoid accumulation of dust or foreign materials. (Page 11)